After returning to Konoha from the Isshiki fight, it's telling that the first thing Sasuke wants to do after the intense battle is see his wife right away, especially when considering how Sasuke appears to have expected to die in that fight.
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Upon his return, he's visibly relieved and thankful to still be alive, glad that he is still living and able to return home to his family.
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For Sasuke, Sakura represents a safe home that he can come back to after the brutal reality of his job.
