It's ironic that the Boruto manga directly addresses this anti-SasuSaku complaint in the Ino/Sakura flower shop scene, where Ino encapsulates fans' concerns/criticism of the relationship: "I could never be in the kind of marriage you have; I could never stand for having a husband so frequently absent". The inference of Sakura's response to Ino's criticism is: "Well I'm not you, and it works for me, so don't project your needs onto me, because we're different people with different needs/wants". Of course Sakura is kind and mild in her response to Ino and doesn't mean it meanly, but the general idea is there.
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I grow tired of fans who self-insert and self-project their own feelings onto Sakura instead of analytically dissecting her actual character. It leads to an inaccurate and false interpretation of the series and of Sakura's character because fans are explaining how they would feel if they were in Sakura's position, not how Sakura feels.
Sakura herself makes it clear she's satisfied with her life. When Sarada mentions that Sasuke should relax at home more (Sarada's indirect way of stating that she wishes Sasuke would hang around the house more often and spend more time with her), Sakura is unperturbed. Sakura looks unmoved, noting that Sasuke's lifestyle works fine for him (making the correlation that Sasuke's lifestyle works fine for her too) and she's content that he visits her late at night. Rather than looking troubled or wistful like she too wished Sasuke would visit the house more, Sakura states that, "this is fine for him" and mentions that Sasuke talks to her late at night. The subtext: Sakura is happy with her marriage and life as long as her husband is happy with his. In that sense, their feelings are connected: when one is happy, the other is happy. When one suffers, the other suffers.
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If anything, Sakura is much happier than she was during her younger years in Part I and Part II, when Sasuke was never around. She was reduced to tears in many moments of Part I and Shippuden. But in Boruto, Sakura virtually never cries. It should be obvious that a huge reason that Sakura is much happier during her era is because of Sasuke. In Boruto, Sasuke is happy, so Sakura is happy as well.
Nothing in Boruto suggests that Sakura's ebullience and vivacity for life has been diminished. She is still bubbly and cheerful and has her playful side (which contrary to popular belief, does emerge around Sasuke as well).